Endocrine Abstracts

Aim: To investigate the possible association of the rs9939609 polymorphism in the FTO gene with obesity in the Republic of Tatarstan (RT).Materials and methods: The study involved 63 adult patients (21 men and 42 women; 38–77 years old) with overweight or obesity and 515 healthy young people (157 men and 358 women; 16–35 years old) with normal weight. We assessed clinical and biochemical parameters (blood lipid profile). The analysis of the rs9...

Aim: To investigate the possible association of the FTO gene rs9939609 polymorphism with different disorders of carbohydrate metabolism in residents of the Republic of Tatarstan.Materials and methods: A total of 237 patients with a single history of hyperglycemia were examined. They underwent an oral glucose tolerance test on a BS-200E Mindray analyzer. 198 patients from the whole cohort had various disorders of carbohydrate metabolism, so they were incl...

Aim: To investigate the effect of the standard dietary recommendations in diabetes mellitus type 2 to the intensity of metabolic processes due to different variants of polymorphism rs1801282 Pro12Ala of the PPARG gene.Materials and methods: 37 patients (11 men and 26 women) in the age of 38–76 years old (the mean age 56.8±9.55 y.o.), with the verified diagnosis of diabetes mellitus type 2 (the mean duration of illness 5.7±3.59 years) and t...